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tlx3 protein expression  (Human Protein Atlas)

 
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    Human Protein Atlas tlx3 protein expression
    Experimental validation of predicted human <t>TLX3</t> binding sequences. Left panel: Prediction of binding preferences for the human TLX3 TF. The top three predicted binding sequences, which were used for EMSA assays, are displayed as well as the consensus binding motif. The sequence highlighted in blue showed binding to TLX3 in the EMSA assay. Right panel: Results of the EMSA assay using sequence #2 (predicted sequence highlighted in blue), referred to as probe. Lane 1: Negative control (probe only). Lane 2: Biotinylated probe. Lane 3: Cold probe (competition assay). Lane 4: Scrambled probe. The yellow circle marks the shifted, bound motif with TLX3.
    Tlx3 Protein Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tlx3+protein+expression/tlx3+protein+expression/pmc04267649-280-7-3
    Average 90 stars, based on 1 article reviews
    tlx3 protein expression - by Bioz Stars, 2026-09
    90/100 stars

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    1) Product Images from "Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes"

    Article Title: Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes

    Journal: Nucleic Acids Research

    doi: 10.1093/nar/gku1228

    Experimental validation of predicted human TLX3 binding sequences. Left panel: Prediction of binding preferences for the human TLX3 TF. The top three predicted binding sequences, which were used for EMSA assays, are displayed as well as the consensus binding motif. The sequence highlighted in blue showed binding to TLX3 in the EMSA assay. Right panel: Results of the EMSA assay using sequence #2 (predicted sequence highlighted in blue), referred to as probe. Lane 1: Negative control (probe only). Lane 2: Biotinylated probe. Lane 3: Cold probe (competition assay). Lane 4: Scrambled probe. The yellow circle marks the shifted, bound motif with TLX3.
    Figure Legend Snippet: Experimental validation of predicted human TLX3 binding sequences. Left panel: Prediction of binding preferences for the human TLX3 TF. The top three predicted binding sequences, which were used for EMSA assays, are displayed as well as the consensus binding motif. The sequence highlighted in blue showed binding to TLX3 in the EMSA assay. Right panel: Results of the EMSA assay using sequence #2 (predicted sequence highlighted in blue), referred to as probe. Lane 1: Negative control (probe only). Lane 2: Biotinylated probe. Lane 3: Cold probe (competition assay). Lane 4: Scrambled probe. The yellow circle marks the shifted, bound motif with TLX3.

    Techniques Used: Biomarker Discovery, Binding Assay, Sequencing, Negative Control, Competitive Binding Assay

    Predicted function of the TLX3 TF. (A) Protein expression levels of TLX3 as reported in the Human Protein Atlas . The tissue types were broadly grouped and the percent of observed expression levels were calculated for the tested subtissues within each category. Detailed expression levels in subtissues are presented in Supplementary Table S9. (B) Ingenuity pathway analysis of observed targets genes of TLX3 obtained with the TF2DNA predicted binding motif. The figure shows the five most significantly enriched networks in the physiological system development and function category. Sphere sizes are proportional (logarithmic scale) to the amount of genes populating the category. The TLX3 target genes that were enriched within this category are listed in Supplementary Table S12.
    Figure Legend Snippet: Predicted function of the TLX3 TF. (A) Protein expression levels of TLX3 as reported in the Human Protein Atlas . The tissue types were broadly grouped and the percent of observed expression levels were calculated for the tested subtissues within each category. Detailed expression levels in subtissues are presented in Supplementary Table S9. (B) Ingenuity pathway analysis of observed targets genes of TLX3 obtained with the TF2DNA predicted binding motif. The figure shows the five most significantly enriched networks in the physiological system development and function category. Sphere sizes are proportional (logarithmic scale) to the amount of genes populating the category. The TLX3 target genes that were enriched within this category are listed in Supplementary Table S12.

    Techniques Used: Expressing, Binding Assay

    Related Articles

    Expressing:

    Article Title: Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes
    Article Snippet: .. According to The Human Protein Atlas , TLX3 protein expression is observed in epithelial cells (squamous, glandular and transitional), hematopoietic, endocrine, messenchimal and other types of cells (Figure and Supplementary Table S9). ..



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    tlx3 protein expression  (Human Protein Atlas)
    90
    Human Protein Atlas tlx3 protein expression
    Experimental validation of predicted human <t>TLX3</t> binding sequences. Left panel: Prediction of binding preferences for the human TLX3 TF. The top three predicted binding sequences, which were used for EMSA assays, are displayed as well as the consensus binding motif. The sequence highlighted in blue showed binding to TLX3 in the EMSA assay. Right panel: Results of the EMSA assay using sequence #2 (predicted sequence highlighted in blue), referred to as probe. Lane 1: Negative control (probe only). Lane 2: Biotinylated probe. Lane 3: Cold probe (competition assay). Lane 4: Scrambled probe. The yellow circle marks the shifted, bound motif with TLX3.
    Tlx3 Protein Expression, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tlx3+protein+expression/tlx3+protein+expression/pmc04267649-280-7-3
    Average 90 stars, based on 1 article reviews
    tlx3 protein expression - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Experimental validation of predicted human TLX3 binding sequences. Left panel: Prediction of binding preferences for the human TLX3 TF. The top three predicted binding sequences, which were used for EMSA assays, are displayed as well as the consensus binding motif. The sequence highlighted in blue showed binding to TLX3 in the EMSA assay. Right panel: Results of the EMSA assay using sequence #2 (predicted sequence highlighted in blue), referred to as probe. Lane 1: Negative control (probe only). Lane 2: Biotinylated probe. Lane 3: Cold probe (competition assay). Lane 4: Scrambled probe. The yellow circle marks the shifted, bound motif with TLX3.

    Journal: Nucleic Acids Research

    Article Title: Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes

    doi: 10.1093/nar/gku1228

    Figure Lengend Snippet: Experimental validation of predicted human TLX3 binding sequences. Left panel: Prediction of binding preferences for the human TLX3 TF. The top three predicted binding sequences, which were used for EMSA assays, are displayed as well as the consensus binding motif. The sequence highlighted in blue showed binding to TLX3 in the EMSA assay. Right panel: Results of the EMSA assay using sequence #2 (predicted sequence highlighted in blue), referred to as probe. Lane 1: Negative control (probe only). Lane 2: Biotinylated probe. Lane 3: Cold probe (competition assay). Lane 4: Scrambled probe. The yellow circle marks the shifted, bound motif with TLX3.

    Article Snippet: According to The Human Protein Atlas , TLX3 protein expression is observed in epithelial cells (squamous, glandular and transitional), hematopoietic, endocrine, messenchimal and other types of cells (Figure and Supplementary Table S9).

    Techniques: Biomarker Discovery, Binding Assay, Sequencing, Negative Control, Competitive Binding Assay

    Predicted function of the TLX3 TF. (A) Protein expression levels of TLX3 as reported in the Human Protein Atlas . The tissue types were broadly grouped and the percent of observed expression levels were calculated for the tested subtissues within each category. Detailed expression levels in subtissues are presented in Supplementary Table S9. (B) Ingenuity pathway analysis of observed targets genes of TLX3 obtained with the TF2DNA predicted binding motif. The figure shows the five most significantly enriched networks in the physiological system development and function category. Sphere sizes are proportional (logarithmic scale) to the amount of genes populating the category. The TLX3 target genes that were enriched within this category are listed in Supplementary Table S12.

    Journal: Nucleic Acids Research

    Article Title: Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes

    doi: 10.1093/nar/gku1228

    Figure Lengend Snippet: Predicted function of the TLX3 TF. (A) Protein expression levels of TLX3 as reported in the Human Protein Atlas . The tissue types were broadly grouped and the percent of observed expression levels were calculated for the tested subtissues within each category. Detailed expression levels in subtissues are presented in Supplementary Table S9. (B) Ingenuity pathway analysis of observed targets genes of TLX3 obtained with the TF2DNA predicted binding motif. The figure shows the five most significantly enriched networks in the physiological system development and function category. Sphere sizes are proportional (logarithmic scale) to the amount of genes populating the category. The TLX3 target genes that were enriched within this category are listed in Supplementary Table S12.

    Article Snippet: According to The Human Protein Atlas , TLX3 protein expression is observed in epithelial cells (squamous, glandular and transitional), hematopoietic, endocrine, messenchimal and other types of cells (Figure and Supplementary Table S9).

    Techniques: Expressing, Binding Assay